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Purpose
Chimeric antigen receptor T-cells (CAR-T) are used to treat a variety of cancer. However, unlike well-defined drugs such as chemicals and antibodies, CAR-T are complex, living therapies. Therefore, it is difficult to objectively assess the potency of CAR-T. The overall objective of this project is to determine immunometabolomic biomarkers that can be measured prior to infusion of CAR-T into patients in order to predict the treatment efficacy for each patient.
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
1,000 grants totalling $348.9M
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