Recipient
Université LavalDepartment
National Research Council CanadaAmount
$100.0K
Province
QCType
G
Agreement Number
956909
Purpose
This Project seeks to produce recombinant St1Cas9 and variants and test their efficiency both in vitro and in vivo. These recombinant gene editing tools will become part of the toolkit the NRC-CGT Program aims to build to facilitate multiplex combinatorial gene editing in induced pluripotent stem cells (iPSCs) and immune cells. Along with the production of SpCas9, MAD7, and potentially Cas12a, the production of St1Cas9 and variants will broaden target flexibility and help to accelerate innovation and discovery cycles in engineered cell and gene therapies.
Université Laval × National Research Council Canada
19 grants totalling $2.4M
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
1,000 grants totalling $348.9M
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